Fitzgerald/Lamin B1 antibody/10R-6722/100 ug
商品编号：
10R-6722-100ug
品牌：
fitzgerald-fii
市场价：
¥12500.00
美元价：
9375.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | MonoclonalLaminB1antibody,Anti-LaminB1antibody,Lamin-B1antibody,LMNB1antibody,ADLDantibody,LMNantibody,LMN2antibody,LMNBantibody,MGC111419antibody,LaminB1,LaminB1,LaminB-1,LaminB1antibody,LaminB-1antibody |
|---|---|
| CrossReactivity | Human,Mouse,Rat |
| Applications | ELISA,IF,IP,WB |
| Immunogen | LaminB1antibodywasraisedinMouseusingrecombinanthumanLaminBastheimmunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | ZL-5 |
| Isotype | IgG1kappa |
| MethodofPurification | LaminB1antibodywaspurifiedbyproteinGpurification. |
| Form&Buffer | SuppliedinPBScontaining1mg/mlBSAand1.5mMsodiumazideand50%glycerol. |
| Concentration | 200ug/ml |
STORAGE&SAFETY:
| Storage | Storeat-20degC.Forlong-termstorage,aliquotandfreezeat-70degC.Avoidrepeatedfreeze/thawcycles. |
|---|
UsageAssayInformation:
| UsageRecommendations | ELISA:0.2-1ug/ml,IF:10-15ug/ml,WB:0.5-2ug/ml |
|---|
GENERALINFORMATION:
| BIOLOGicalSignificance | LaminsareclassifiedintoAandBtypeisoforms.Specifically,fourdistinctlaminisoformshavebeenidentified:A,B1,B2,andC.LaminAandCarealternativelysplicedproductsofasinglegene,whereaslaminB1andB2areencodedbydistinctgenes.Duringmitosis,laminsarephosphorylatedbyp34cdc2andsolubilizedpriortochromosomecondensationandnuclearbreakdown.AdirectroleforlaminsinchromosomecondensationissuggestedbythefactthatlaminBbindstospecificDNAsequencemotifstermedmatrixattachmentregions(MARs).Marsmediatetheinteractionofchromatinwiththenuclearmatrix.Importantly,someofthesameprocessesthatinvolvemitoticchromosomecondensationandnuclearenvelopbreakdownarealsoactivatedduringapoptosis.Itappearsthatchromosomecondensationduringapoptosisisaccompaniedbydegradationoflaminprotein.LamindegradationoccurspriortoDNAfragmentationandthisdegradationisusefulasanapoptoticMarker. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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