Fitzgerald/ROCK 1 antibody/10R-6746/100 ug
商品编号:
10R-6746-100ug
品牌:
fitzgerald-fii
市场价:
¥12500.00
美元价:
9375.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
OVERVIEW:
Synonyms | MonoclonalROCK1antibody,Anti-ROCK1antibody,ROCK-1,Rhoassociatedcoiledcoilcontainingproteinkinase1antibody,ROCK1antibody,ROCK-1antibody,ROCK1,ROCK-1antibody,ROCK1 |
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CrossReactivity | Human,Mouse |
Applications | WB |
Immunogen | ROCK1antibodywasraisedinMouseusingsyntheticpeptidecorrespondingtothecaspase-3cleavagesiteastheimmunogen. |
SPECIFICATIONS:
Host | Mouse |
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Clone | 12M03 |
Isotype | IgG |
MethodofPurification | ROCK1antibodywaspurifiedbyProteinGpurification. |
Form&Buffer | SuppliedinPBSbuffer,pH7.2,containing50%glycerol,1%BSA,0.02%thimerosal. |
Concentration | 500ug/ml |
STORAGE&SAFETY:
Storage | Storeat-20degC.Forlong-termstorage,aliquotandfreezeat-70degC.Avoidrepeatedfreeze/thawcycles. |
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UsageAssayInformation:
UsageRecommendations | WB:1-4ug/ml |
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GENERALINFORMATION:
BIOLOGicalSignificance | ROCK1hasbeenfoundtobeanewcaspase3substrate.ROCK1consistsofanaminoterminalkinasedomainandaninhibitorycysteine/histidinerichCterminaldomain.Duringapoptosis,ROCK1iscleavedbycaspase3attheconservedDETD1113/GsequenceanditsCterminalinhibitorydomainisremoved,resultinginderegulatedandconstitutivekinaseactivity.Thecaspase3mediatedcleavageandactivationofROCK1inducesphosphorylationofmlCandmembraneblebbing,theearlyeventsintheexecutionphaseofapoptosis. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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