Fitzgerald/CD49e antibody/10R-6414/50 ug
商品编号：
10R-6414-50ug
品牌：
fitzgerald-fii
市场价：
¥2800.00
美元价：
2100.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal CD49e antibody, Anti-CD49e antibody, CD-49e, ITGA5 antibody, CD49e, CD-49e antibody, CD 49e, VLA5A antibody, CD 49e antibody, Integrin a5 antibody |
|---|---|
| Specificity | Mouse |
| Applications | FC, Functional Assay, IP |
| Assay Information | A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 105 to 108 cells/test. It is recommended that the antibody be carefully titrated for optimal /formance in the assay of interest. |
SPECIFICATIONS:
| Host | Hamster |
|---|---|
| Clone | HMa5-1 |
| Isotype | IgG |
| Method of Purification | CD49e antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer. |
| Concentration | 500 ug/ml |
STORAGE & SAFETY:
| Storage | Store at 2-8 deg C. Do not freeze. Protect from light. |
|---|
Usage Assay Information:
| Usage Recommendations | FC: = 0.5 ug/test |
|---|
GENERAL INFORMATION:
| Biological Significance | The HM alpha5-1 monoclonal antibody reacts with mouse and rat CD49e, also known as integrin alpha5 or VLA-5A. CD49e is a member of the integrin alpha chain family, and binds with CD29 to form the receptor VLA-5, which binds the ligands fibronectin and fibrinogen. CD49e is a type I, single-pass membrane protein, with a molecular weight of 135 kDa, and is expressed on multiple cell types including thymocytes, mast cells, activated T cells and splenic B cells. In addition to its role in adhesion, VLA-5 contributes to T-cell co-stimulation. The HM alpha5-1 monoclonal antibody has been demonstrated to interfere with VLA-5-mediated cell adhesion, and with the degranulation of IgE-sensitized rat RBL cells stimulated on fibronectin-coated plates. Furthermore, HM alpha5-1 injected into mice subcutaneously, along with anti-CD49d and anti-CD61, is able to inhibit passive cutaneous anaphylaxis. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
联络我们
