Fitzgerald/CCR7 antibody/10R-6507/100 ug
商品编号：
10R-6507-100ug
品牌：
fitzgerald-fii
市场价：
¥4700.00
美元价：
3525.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal CCR7 antibody, Anti-CCR7 antibody, C-C chemokine receptor type 7 antibody, CCR 7 antibody, CCR7, CCR-7, MIP-3 beta Receptor antibody, EBI-1 antibody, CCR 7, CMKBR7 antibody, CCR-7 antibody, CCR-7 antibody |
|---|---|
| Specificity | Human |
| Applications | FC, IHC, IP, WB |
| Assay Information | A test is defined as the amount (ug) of antibody that will stain a cell sample in a final volume of 100 ul. Cell number should be determined empirically but can range from 105 to 108 cells/test. It is recommended that the antibody be carefully titrated for optimal /formance in the assay of interest. |
SPECIFICATIONS:
| Host | Rat |
|---|---|
| Clone | 3D12 |
| Isotype | IgG2a kappa |
| Method of Purification | CCR7 antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in aqueous buffer with 0.09% sodium azide, may contain carrier protein/stabilizer. |
| Concentration | 500 ug/ml |
STORAGE & SAFETY:
| Storage | Store at 2-8 deg C. Do not freeze. Protect from light. |
|---|
Usage Assay Information:
| Usage Recommendations | FC: = 0.5 ug/test |
|---|
GENERAL INFORMATION:
| Biological Significance | The 3D12 monoclonal antibody reacts with human CCR7, also known as EBI-1 and CD197. CCR7 is a member of the G-protein-coupled chemokine receptor family with seven membrane-spanning domains and functions as a receptor for 6Ckine/SLC, CCL19 and CCL21. CCR7 has been shown to be internalized via clathrin-coated pits and the majority recycled back to the plasma membrane. CCR7 is expressed on T cells and can be used to distinguish populations of naïve from central and effector memory T cells. CCR7 has been shown to play a role in migration of memory T cells to inflamed tissue. Expression of CCR7 is also found on DC?s. During DC maturation CCR7 expression increases and is thought to be involved in a variety of functions: chemotaxis to the lymph node, cellular architecture, rate of endocytosis, survival and maturation. Expression of CCR7 on the cell surface can be down regulated upon ligand binding. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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