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当前位置: 首页 > 产品中心 > Polyclonal_antibody > Fitzgerald/ERCC1 antibody/10R-6925/100 ul
商品详细Fitzgerald/ERCC1 antibody/10R-6925/100 ul
Fitzgerald/ERCC1 antibody/10R-6925/100 ul
Fitzgerald/ERCC1 antibody/10R-6925/100 ul
商品编号: 10R-6925-100ul
品牌: fitzgerald-fii
市场价: ¥12240.00
美元价: 9180.00
产地: 美国(厂家直采)
公司:
产品分类: 多克隆抗体
公司分类: Polyclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

OVERVIEW:

Synonyms Monoclonal ERCC1 antibody, Anti-ERCC1 antibody, COFS4 antibody, RAD10 antibody, UV20 antibody, ERCC1, ERC 1c, ERC-1c, ERC 1c antibody, ERC-1c antibody
Cross Reactivity Human
Applications FC, IF, WB
Immunogen ERCC1 antibody was raised in Mouse using full length human recombinant protein of human ERCC1 produced in HEK293T cell as the immunogen.

SPECIFICATIONS:

Host Mouse
Clone 5E6
Isotype IgG2a
Method of Purification ERCC1 antibody was purified by affinity chromatography.
Form & Buffer Supplied in PBS buffer, pH 7.3, containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Concentration 0.5-1 mg/ml

STORAGE & SAFETY:

Storage Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.

Usage Assay Information:

Usage Recommendations FC: 1:100, IF: 1:100, WB: 1:500-2000

GENERAL INFORMATION:

Biological Significance The product of this gene functions in the nucleotide excision repair pathway, and is required for the repair of DNA lesions such as those induced by UV light or formed by electrophilic compounds including cisplatin. The encoded protein forms a heterodimer with the XPF endonuclease (also known as ERCC4), and the heterodimeric endonuclease catalyzes the 5' incision in the process of excising the DNA lesion. The heterodimeric endonuclease is also involved in recombinational DNA repair and in the repair of inter-strand crosslinks. Mutations in this gene result in cerebrooculofacioskeletal syndrome, and polymorphisms that alter expression of this gene may play a role in carcinogenesis.
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。