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当前位置: 首页 > 产品中心 > Polyclonal_antibody > Fitzgerald/Ubiquitin+1 antibody/10R-7468/100 ul
商品详细Fitzgerald/Ubiquitin+1 antibody/10R-7468/100 ul
Fitzgerald/Ubiquitin+1 antibody/10R-7468/100 ul
Fitzgerald/Ubiquitin+1 antibody/10R-7468/100 ul
商品编号: 10R-7468-100ul
品牌: fitzgerald-fii
市场价: ¥6720.00
美元价: 5040.00
产地: 美国(厂家直采)
公司:
产品分类: 多克隆抗体
公司分类: Polyclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

OVERVIEW:

SynonymsMonoclonalUbiquitin+1antibody,Anti-Ubiquitin+1antibody,Ubiquitin+1,Ubiquitin+1antibody,Ub+1antibody,Ubiquitin+-1antibody,Ubiquitin+1,Ubiquitin+-1
CrossReactivityHuman
ApplicationsIP,WB
ImmunogenUbiquitin+1antibodywasraisedinMouseusingsyntheticpeptide(KLHcoupled)correspondingtoC-terminalresiduesofhumanUbiquitin+1astheimmunogen.

SPECIFICATIONS:

HostMouse
Clone40B3
IsotypeIgG1kappa
MethodofPurificationUbiquitin+1antibodywaspurifiedbyaffinitychromatography.
Form&BufferSuppliedinPBSbuffer(withoutmg2+andCa2+),pH7.4,150mMNaCland50%glycerol.
Concentration1mg/ml

STORAGE&SAFETY:

StorageStoreat4degCforshorttermstorage.Aliquotandstoreat-20degCforlongtermstorage.Avoidrepeatedfreeze/thawcycles..

UsageAssayInformation:

UsageRecommendationsWB:1:500-1000,IP1-2ul/400ulcelllysates

GENERALINFORMATION:

BIOLOGicalSignificanceUbiquitin+1isanovelmutantformofubiquitinthatcanbeproducedthroughaprocessknownasmolecularframeshift.Ub+1canbepolyubiquitinatedtoproduceaberrantpolyubiquitinchainsthatinhibitthe26Sproteasome.Especiallyub+1isaccumulatedinaggregatescontainingamyloid-betaandphosphorylated-tau.ElevatedexpressionofUb+1mRNAandproteinhasbeenobservedinthebrainsofpatientswithAlzheimer"sdisease.Alsoub+1actsasanaggravatingfactorinpolyglutamine-inducedneurodegeneration.
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。