Fitzgerald/Superoxide Dismutase 1 antibody/10R-7482/100 ul
商品编号：
10R-7482-100ul
品牌：
fitzgerald-fii
市场价：
¥6720.00
美元价：
5040.00
产品分类：
多克隆抗体
公司分类：
Polyclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal Superoxide Dismutase 1 antibody, Anti-Superoxide Dismutase 1 antibody, ALS1 antibody, Superoxide Dismutase-1 antibody, Amyotrophic lateral sclerosis 1 antibody, Superoxide Dismutase-1, ALS antibody, Superoxide Dismutase 1, IPOA antibody, Superoxide Dismutase 1 antibody, Superoxide Dismutase 1, hSod1 antibody |
|---|---|
| Cross Reactivity | Human |
| Applications | IP |
| Immunogen | Superoxide Dismutase 1 antibody was raised in Mouse using recombinant human protein purified from E.coli as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 72B1 |
| Isotype | IgG1 kappa |
| Method of Purification | Superoxide Dismutase 1 antibody was purified by affinity chromatography. |
| Form & Buffer | Supplied in PBS buffer (without mg2+ and Ca2+), pH 7.4, 150mM NaCl and 50% glycerol. |
| Concentration | 1 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C for short term storage. Aliquot and store at -20 deg C for long term storage. Avoid repeated freeze/thaw cycles.. |
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Usage Assay Information:
| Usage Recommendations | IP 1-2ul/400ul lysates |
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GENERAL INFORMATION:
| Biological Significance | Superoxide dismutase (SOD) is an antioxidant enzyme involved in the defense system against reactive oxygen species (ROS). SOD catalyzes the dismutation reaction of superoxide radical anion (O2-) to hydrogen peroxide, which is then catalyzed to innocuous O2 and H2O by glutathione peroxidase and catalase. Several classes of SOD have been identified. These include intracellular copper, zinc SOD (Cu, Zn-SOD/SOD-1), mitochondrial manganese SOD (Mn-SOD/SOD-2) and extracellular Cu, Zn-SOD (EC-SOD/SOD-3). SOD1 is found in all eukaryotic species as a homodimeric 32 kDa enzyme containing one each of Cu and Zn ion per subunit . The manganese containing 80 kDa tetrameric enzyme SOD2, is located in the mitochondrial matrix in close proximity to a primary endogenous source of superoxide, the mitochondrial respiratory chain. SOD3 is a heparin-binding multimer of disulfide-linked dimers, primarily expressed in human lungs, vessel walls and airways. SOD4 is a copper chaperone for superoxide dismutase (CCS), which specifically delivers Cu to copper/zinc superoxide dismutase. CCS may activate copper/zinc superoxide dismutase through direct insertion of the Cu cofactor. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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