Fitzgerald/Vitamin D3 antibody/10R-7552/100 ug
商品编号：
10R-7552-100ug
品牌：
fitzgerald-fii
市场价：
¥9780.00
美元价：
7335.00
产品分类：
多克隆抗体
公司分类：
Polyclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | MonoclonalVitaminD3antibody,Anti-VitaminD3antibody,VitaminD3,VitaminD3antibody,VitaminDantibody,D3antibody,25-hydroxyvitaminD3antibody,25(OH)D3antibody,VitaminD3,VitaminD-3,VitaminD-3antibody |
|---|---|
| Applications | FC |
| Immunogen | VitaminD3antibodywasraisedinmouseusing25-HydroxyvitaminD3astheimmunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 685503 |
| Isotype | IgG1 |
| Form&Buffer | Suppliedlyophilizedfroma0.2µmfilteredsolutioninPBSwithTrehalose. |
STORAGE&SAFETY:
| Storage | Storeat-20to-70degC |
|---|
GENERALINFORMATION:
| BIOLOGicalSignificance | 25hydroxyvitaminD3(25(OH)D3)issynthesizedintheliverandistheprimarycirculatingformofvitaminD.Itsbloodconcentration,whichreflects25(OH)D3producedbyexposuretoultravioletB,aswellasdietaryandvitaminDsupplementation,isfelttobethebestindicatorofvitaminDstatus.25(OH)D3ismetabolizedto1alpha,25(OH)2D3intheproximaltubularcellsofthekidneybytheenzyme1alphahydroxylase.ThevitaminDstructureissimilartothatofclassicsteroidhormones,suchasestrADIol,cortisol,andaldosteroneinthattheyhavethesamerootcyclopentanoperhydrophenanthreneringstructure.Ithasbeenshownthattheactivesteroidhormone1alpha,25(OH)2D3isessentialforlifeinhigheranimals.Besidesplayingimportantrolesincalciumhomeostasisandbonemineralmetabolism,itisnowknowntoplayaroleincellulardifferentiation,inhibitionofcellgrowth,immuneregulationandthepreventionofneoplastictransformation.TheactiveformofvitaminD3,1alpha,25(OH)2D3,actsboththroughitscellularreceptor,thevitaminDreceptor(VDR),andthroughotherextrarenaltargetsinanautocrineandparacrinemannerwhere1alphahydroxylaseispresent. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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