菲茨杰拉德/耐热肠毒素抗体/10-1018/500微克
商品编号：
10-1018-500ug
品牌：
fitzgerald-fii
市场价：
¥5900.00
美元价：
4425.00
产品分类：
多克隆抗体
公司分类：
Polyclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal Heat Labile Enterotoxin antibody, Anti-Heat Labile Enterotoxin antibody, Enterotoxin antibody |
|---|---|
| Specificity | Reactive to Heat-labile enterotoxin (LT) |
| Cross Reactivity | Cross reactive to Cholera toxin (CT) |
| Applications | ELISA |
| Immunogen | Heat Labile Enterotoxin antibody was raised in mouse using Heat-labile enterotoxin as the immunogen. |
| Assay Information | Use 10-1018 as the capture antibody with 10-1019 as the detection antibody in ELISA |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | M120534 |
| Isotype | IgG1 |
| Purity | > 95% pure |
| Method of Purification | Heat Labile Enterotoxin antibody was purified by Protein A or G affinity purification |
| Form & Buffer | Supplied as a liquid in PBS, pH 7.4, 3mM KCl, 1.5mM KH2PO4, 140mM NaCl, 8.0mM Na2HPO4 |
| Concentration | 1-3 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C for short term or -20 deg C for longer storage. Avoid repeated freeze/thaw cycles. |
|---|---|
| Biohazard Information | This product contains sodium azide as a preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling. |
GENERAL INFORMATION:
| Biological Significance | Heat-labile enterotoxin is a type of labile toxin found in Escherichia coli that is inactivated at high temperatures. It acts similarly to the cholera toxin by raising cAMP levels through ADP-ribosylation of the alpha-subunit of a Gs protein leading to the constitutive activation of adenylate cyclase. Elevated cAMP levels stimulate secretion of Chloride ions and water from the enterocyte into the gut lumen, thus causing watery diarrhea. In addition to its effects on chloride secretion, which involve the same steps as the effects of cholera toxin, heat-labile enterotoxin binds additional substrates: lipopolysaccharide on the surface of E. coli cells and A-type blood antigens. The importance of these binding events is not yet known. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
联络我们
