菲茨杰拉德/IRS抗体/10R-8023/100微克
商品编号：
10R-8023-100ug
品牌：
fitzgerald-fii
市场价：
¥8760.00
美元价：
6570.00
产品分类：
多克隆抗体
公司分类：
Polyclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | MonoclonalIRSantibody,anti-IRSantibody,Phospho-IRSSer616antibody,phospho-IRSantibody,IRSantibody,IRSantibody,IRSantibody,AntiIRSantibody,phospho-IRSantibody,Phospho-IRSSer616antibody |
|---|---|
| CrossReactivity | Human |
| Applications | ELISA,WB |
| Immunogen | IRSantibodywasraisedinMouseusingsyntheticpeptidephosphorylatedatSer616siteastheimmunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | HIR-B1 |
| Isotype | IgG1 |
| MethodofPurification | IRSantibodywaspurifiedbyaffinitychromatography |
| Form&Buffer | SuppliedinPBSbufferwith0.05%(W/V)sodiumazide |
| Concentration | 1mg/ml |
STORAGE&SAFETY:
| Storage | Storeat4degCforshorttermstorage.Aliquotandstoreat-20degCforlongtermstorage.Avoidrepeatedfreeze/thawcycles. |
|---|
GENERALINFORMATION:
| BIOLOGicalSignificance | InsulinreceptorsubstratessubtypesareresponsIBLeforseveralinsulinrelatedactivities,suchasglucosehomeostasis,cellgrowth,celltransformation,apoptosisandinsulinsignaltransduction.ThebalancebetweenSer/ThrphosphorylationofIRShasbeendemonstratedtobeanimportantregulatorofinsulinsignaling.IRS1hasalsobeenshowntobeconstitutivelyactivatedincancerssuchasbreastcancer,Wilm’stumors,andadrenalcorticalcarcinomas.DoesnotrecognizeIRSpeptideNOTphosphorylatedatSer616andwillnotrecognizeIRSpeptidephosphorylatedatTyr183.Alsodoesnotreactwithriboflavincarrierproteinwhichisknowntohavemultiplephosphategroups. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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