Fitzgerald/PTP1B antibody/10R-8026/100 ug
商品编号：
10R-8026-100ug
品牌：
fitzgerald-fii
市场价：
¥8760.00
美元价：
6570.00
产品分类：
多克隆抗体
公司分类：
Polyclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | MonoclonalPTP1Bantibody,anti-PTP1Bantibody,Tyrosine-proteinphosphatasenon-receptortype1antibody,Protein-tyrosinephosphatase1Bantibody,PTPB-1antibody,PTP-1Bantibody,PTPB1antibody,PTPB1,PTP1Bantibody,PTPB-1,PTP1B |
|---|---|
| CrossReactivity | Human,Mouse |
| Applications | ELISA,WB |
| Immunogen | PTP1BantibodywasraisedinMouseusingrecombinantproteinencodingaminoacids1-321ofhumanPTP1Bastheimmunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 107AT531 |
| Isotype | IgG1 |
| MethodofPurification | PTP1Bantibodywaspurifiedbyaffinitychromatography |
| Form&Buffer | SuppliedinPBSbufferwith0.09%(W/V)sodiumazide |
| Concentration | 250ug/ml |
STORAGE&SAFETY:
| Storage | Storeat4degCforshorttermstorage.Aliquotandstoreat-20degCforlongtermstorage.Avoidrepeatedfreeze/thawcycles. |
|---|
UsageAssayInformation:
| UsageRecommendations | ELISA:0.25ug/ml,WB:0.5-2.5ug/ml |
|---|
GENERALINFORMATION:
| BIOLOGicalSignificance | PTP1Bisthefoundingmemberoftheproteintyrosinephosphatasefamily,whichwasisolatedandidentifiedbasedonitsenzymaticactivityandaminoacidsequence.PTPscatalyzethehydrolysisofthephosphatemonoestersspecificallyontyrosineresidues.MembersofthePTPfamilyshareahighlyconservedcatalyticmotif,whichisessentialforthecatalyticactivity.PTPsareknowntobesignalingmoleculesthatregulateavarietyofcellularprocessesincludingcellgrowth,differentiation,mitoticcycle,andoncogenictransformation.ThisPTPhasbeenshowntoactasanegativeregulatorofinsulinsignalingbydephosphorylatingthephosphotryosineresiduesofinsulinreceptorkinase.ThisPTPwasalsoreportedtodephosphorylateepidermalgrowthfactorreceptorkinase,aswellasJAK2andTYK2kinases,whichimplicatedtheroleofthisPTPincellgrowthcontrol,andcellresponsetointerferonstimulation. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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