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当前位置: 首页 > 产品中心 > Polyclonal_antibody > Fitzgerald/Heparan Sulphate Proteoglycan antibody/10R-8070/100 ug
商品详细Fitzgerald/Heparan Sulphate Proteoglycan antibody/10R-8070/100 ug
Fitzgerald/Heparan Sulphate Proteoglycan antibody/10R-8070/100 ug
Fitzgerald/Heparan Sulphate Proteoglycan antibody/10R-8070/100 ug
商品编号: 10R-8070-100ug
品牌: fitzgerald-fii
市场价: ¥7000.00
美元价: 5250.00
产地: 美国(厂家直采)
公司:
产品分类: 多克隆抗体
公司分类: Polyclonal_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

OVERVIEW:

Synonyms Monoclonal Heparan Sulphate Proteoglycan antibody, Anti-Heparan Sulphate Proteoglycan antibody, Heparan Sulphate Proteoglycan, HSPG antibody, HSPG
Specificity Recognizes domain IV of the core protein of the large heparan sulphate proteoglycan or perlecan. The reactivity is independent of the galactosaminoglycan moieties. Therefore, the epitope is not sensitive to heparitinase treatment
Cross Reactivity Bovine, Human, Mouse, Rat
Applications IHC, IHC-F, IHC-P, IP, WB
Immunogen Heparan Sulphate Proteoglycan antibody was raised in Rat using high molecular mass material derived from the Engelbreth-Holm-Swarm (EHS) tumor matrix containing laminin, entactin and HSPG as the immunogen.

SPECIFICATIONS:

Host Rat
Clone A7L6
Isotype IgG2a
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage Assay Information:

Usage Recommendations IHC: 1:25-1:200, WB: 1:100-1:1000

GENERAL INFORMATION:

Biological Significance Proteoglycans are macromolecules consisting of a variety of core proteins with covalently attached one or several polysaccharide chains of the glycosaminoglycan type (heparan sulphate, heparin, chondroitin sulphate, dermatan sulphate or keratan sulphate). At least two forms of basement membrane heparan sulphate proteoglycan (HSPG) have been identified. One with a large core protein (> 400 kD) and one with a small core protein (30 kD). The large HSPG is probably the most abundant basement membrane proteoglycan. It is located predominantly in the lamina lucida, where it forms clustered aggregates and interacts with other basement membrane components to form the matrix. In addition, it also plays a critical role in attachment of cells to the basal membrane via integrin receptors.
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。