Fitzgerald/Lamin A/C antibody/10R-8082/100 ug
商品编号：
10R-8082-100ug
品牌：
fitzgerald-fii
市场价：
¥7780.00
美元价：
5835.00
产品分类：
多克隆抗体
公司分类：
Polyclonal_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal Lamin A/C antibody, Anti-Lamin A/C antibody, Lamin A antibody, Lamin C antibody, Lamin A/C |
|---|---|
| Specificity | Reacts with an epitope located between residues 319-566 in lamin A and C |
| Cross Reactivity | Bovine, Canine, Hamster, Human, Mouse, Rat, Sheep |
| Applications | FC, IHC, IHC-F, WB |
| Immunogen | Lamin A/C antibody was raised in Mouse using purified rat liver lamins as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 131C3 |
| Isotype | IgG1 |
| Form & Buffer | Supplied in PBS containing 0.09% sodium azide |
Usage Assay Information:
| Usage Recommendations | FC: 1:100-1:200, IHC: 1:100-1:200, WB: 1:100-1:1000 |
|---|
GENERAL INFORMATION:
| Biological Significance | Lamins are structural protein components of the nuclear lamina, a protein network underlying the inner nuclear membrane that determines nuclear shape and size. There are three types of lamins, A, B and C. The lamin A/C (LMNA) gene contains 12 exons. Alternative splicing within exon 10 gives rise to two different mRNAs that code for pre-lamin A and lamin C. Lamin A/C mapped to 1q21.2-q21.3 and mutations in this gene cause a variety of human diseases including Emery-Dreifuss muscular dystrophy, dilated cardiomyopathy and Hutchinson-Gilford progeria syndrome. Lamin A/C deficiency is thus associated with both defective nuclear mechanics and impaired mechanically activated gene transcription. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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