Fitzgerald/ERBB2抗体/10R-8110/100微克
商品编号：
10R-8110-100ug
品牌：
fitzgerald-fii
市场价：
¥8500.00
美元价：
6375.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal ERBB2 antibody, Anti-ERBB2 antibody, c-neu antibody, erbb2 antibody, Her-2 Neu antibody, her-2/neu antibody, Her2 antibody, Her2 Neu antibody, Her2/Neu antibody, herstatin antibody, neu oncogene antibody, oncogene ngl antibody, p185erbb2 antibody, tkr1 antibody, tyrosine kinase r antibody, ERBB 2 antibody, ERBB-2 antibody, ERBB 2, ERBB-2, ERBB2 |
|---|---|
| Specificity | Reacts equally well with the wild type as well as the mutant (oncogenic) form of the c-erbB-2/HER-2/neu protein, but preferentially recognizes the unphosphorylated form of this protein |
| Cross Reactivity | Human, Monkey, Mouse, Rat |
| Applications | IHC-F, IHC-P, IP, WB |
| Immunogen | ERBB2 antibody was raised in Mouse using a synthetic peptide TAENPEYLGLDVPV corresponding to amino acid residues 1242-1255 of the C-terminus of the human c-erbB-2/HER-2/neu protein This sequence is identical in rat neu protein as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 3B5 |
| Isotype | IgG1 |
| Form & Buffer | Supplied in PBS containing 0.09% sodium azide |
Usage Assay Information:
| Usage Recommendations | IHC: 1:100-1:1000, WB: 1:250-1:1000 |
|---|
GENERAL INFORMATION:
| Biological Significance | In the nucleus is involved in transcriptional regulation. Associates with the 5'-TCAAATTC-3' sequence in the PTGS2/COX-2 promoter and activates its transcription. Implicated in transcriptional activation of CDKN1A; the function involves STAT3 and SRC. Involved in the transcription of rRNA genes by RNA Pol I and enhances protein synthesis and cell growth. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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