Fitzgerald/Transferrin Receptor antibody/10R-8123/100 ug
商品编号：
10R-8123-100ug
品牌：
fitzgerald-fii
市场价：
¥7900.00
美元价：
5925.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal Transferrin Receptor antibody, Anti-Transferrin Receptor antibody, CD71 antibody, CD71 antigen antibody, p90 antibody, sTfR antibody, T9 antibody, TFR 1 antibody, TFR antibody TFR1 antibody, TFRC antibody, TR antibody, Transferrin receptor (p90 CD71) antibody, Transferrin Receptor Protein 1 antibody, TRFR antibody , Transferrin Receptor |
|---|---|
| Specificity | Reacts with the transferrin receptor, a 180-190 kD transmembrane glycoprotein which exists as a 95 kD homodimer with interchain disulfide bond |
| Cross Reactivity | Human |
| Applications | FC, IHC-F, IP, WB |
| Immunogen | Transferrin Receptor antibody was raised in Mouse using human T-cells as the immunogen. |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 66IG10 |
| Isotype | IgG1 |
| Form & Buffer | Supplied in PBS containing 0.09% sodium azide |
Usage Assay Information:
| Usage Recommendations | Optimal dilution should be determined by titration |
|---|
GENERAL INFORMATION:
| Biological Significance | Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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