
Fitzgerald/HLADQ antibody/10R-8138/100 ug
商品编号:
10R-8138-100ug
品牌:
fitzgerald-fii
市场价:
¥7900.00
美元价:
5925.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
OVERVIEW:
Synonyms | Monoclonal HLADQ antibody, HLADQ antibody, CD antibody, CELIAC1 antibody, DC 4 alpha chain antibody, DC alpha antibody, DQ A1 antibody, Gluten sensitive enteropathy (celiac disease) antibody, GSE antibody, HLA-DQ antibody, HLA DQ antibody, HLADQ |
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Specificity | Reacts with a monomorphic determinant on HLA-DQ (MHC class II) |
Cross Reactivity | Human, Swine |
Applications | FC, IHC-F, IP |
Immunogen | HLADQ antibody was raised in Mouse using human HLADQ as the immunogen. |
SPECIFICATIONS:
Host | Mouse |
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Clone | NKI(SPV)L3 |
Isotype | IgG2a |
Form & Buffer | Supplied in PBS containing 0.09% sodium azide |
Usage Assay Information:
Usage Recommendations | Optimal dilution should be determined by titration |
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GENERAL INFORMATION:
Biological Significance | HLADQ is a cell surface receptor type protein found on antigen presenting cells. DQ is an alphabeta heterodimer of the MHC Class II type. The alpha and beta chains are encoded by HLA-DQA1 and HLA-DQB1, respectively. These two loci are adjacent to each other on chromosome 6p21.3. Both the alpha-chain and beta-chain vary greatly. A person often produces two alpha-chain and two beta-chain variants and thus 4 DQ isoforms. The DQ loci are in close genetic linkage to HLA-DR but less closely linked to HLA-DP, HLA-A, HLA-B and HLA-C. DQ functions on antigen presenting cells, and is an antigen presenting molecule. Different DQ isoforms can bind to and present different antigens to T-cells. In this process T-cells are stimulated to grow and can signal B-cells to produce antibodies. DQ functions in recognizing and presenting foreign antigens (proteins derived from potential pathogens). |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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