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当前位置: 首页 > 产品中心 > Functional_antibody > Fitzgerald/HLADQ antibody/10R-8138/100 ug
商品详细Fitzgerald/HLADQ antibody/10R-8138/100 ug
Fitzgerald/HLADQ antibody/10R-8138/100 ug
Fitzgerald/HLADQ antibody/10R-8138/100 ug
商品编号: 10R-8138-100ug
品牌: fitzgerald-fii
市场价: ¥7900.00
美元价: 5925.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

OVERVIEW:

Synonyms Monoclonal HLADQ antibody, HLADQ antibody, CD antibody, CELIAC1 antibody, DC 4 alpha chain antibody, DC alpha antibody, DQ A1 antibody, Gluten sensitive enteropathy (celiac disease) antibody, GSE antibody, HLA-DQ antibody, HLA DQ antibody, HLADQ
Specificity Reacts with a monomorphic determinant on HLA-DQ (MHC class II)
Cross Reactivity Human, Swine
Applications FC, IHC-F, IP
Immunogen HLADQ antibody was raised in Mouse using human HLADQ as the immunogen.

SPECIFICATIONS:

Host Mouse
Clone NKI(SPV)L3
Isotype IgG2a
Form & Buffer Supplied in PBS containing 0.09% sodium azide

Usage Assay Information:

Usage Recommendations Optimal dilution should be determined by titration

GENERAL INFORMATION:

Biological Significance HLADQ is a cell surface receptor type protein found on antigen presenting cells. DQ is an alphabeta heterodimer of the MHC Class II type. The alpha and beta chains are encoded by HLA-DQA1 and HLA-DQB1, respectively. These two loci are adjacent to each other on chromosome 6p21.3. Both the alpha-chain and beta-chain vary greatly. A person often produces two alpha-chain and two beta-chain variants and thus 4 DQ isoforms. The DQ loci are in close genetic linkage to HLA-DR but less closely linked to HLA-DP, HLA-A, HLA-B and HLA-C. DQ functions on antigen presenting cells, and is an antigen presenting molecule. Different DQ isoforms can bind to and present different antigens to T-cells. In this process T-cells are stimulated to grow and can signal B-cells to produce antibodies. DQ functions in recognizing and presenting foreign antigens (proteins derived from potential pathogens).
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。