Fitzgerald/Bid antibody/10R-8491/100 ul
商品编号：
10R-8491-100ul
品牌：
fitzgerald-fii
市场价：
¥5900.00
美元价：
4425.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | MonoclonalBidantibody,Anti-Bidantibody,BIDantibody,BH3interactingdomaindeathagoNISTantibody,apopticdeathagonistantibody,apoptoticdeathagonistBIDantibody,BH3-interactingdomaindeathagonistantibody,BIDisoformES(1b)antibody,BIDisoformL(2)antibody,BIDisoformSi6antibody,BOS_6089antibody,desmocollintype4antibody,FP497antibody,HumanBIDcodingsequenceantibody,p22BIDantibody,RCJMB04_7d15antibody,xbidantibody |
|---|---|
| CrossReactivity | Human |
| Applications | WB |
| Immunogen | BidantibodywasraisedinMouseusingarecombinanthumanproteinpurifiedfromE.coli(His-Bid)astheimmunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 21F10 |
| Isotype | IgG2akappa |
| MethodofPurification | Bidantibodywaspurifiedbyammoniumsulfateprecipitation |
| Form&Buffer | SuppliedinliquidforminHEPESbufferwith0.15MNaCl,0.01%BSA,0.03%sodiumazide,and50%glycerol |
STORAGE&SAFETY:
| Storage | Aliquotandstorefor1yearat-20degC,avoidfreeze/thawcycles |
|---|
UsageAssayInformation:
| UsageRecommendations | WB:1:10000 |
|---|
GENERALINFORMATION:
| BIOLOGicalSignificance | BidconsistsofonlyoneBcl-2homologydomain,BH3.BidcleavagetotBid(truncatedBid)activatesapoptoticpathwayatthemitochondriallevel.CleavageofcytosolicBidandsubsequentmitochondrialtranslocationhavebeendetectedinneuronalcelldeathrelatedtoacuteorchronicneurodegeneration.PharmacologicalinhibitionofBidcanbeapromisingtherapeuticstrategyinneurologicaldiseaseswhereprogrammedcelldeathisprominent.AfterBidactivationandmitochondrialtranslocation,themostprominentdownstreammechanismsofBid-dependentneuronalapoptosisinvolvedisruptionofmitochondrialmembraneintegrityandintracellularcalciumhomoeostasisandthereleaseofpro-apoptoticmitochondrialfactorssuchascytochromec. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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