Fitzgerald/Brutons tyrosine kinase antibody/10R-8474/100 ul
商品编号：
10R-8474-100ul
品牌：
fitzgerald-fii
市场价：
¥5900.00
美元价：
4425.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal Brutons tyrosine kinase antibody, Anti-Brutons tyrosine kinase antibody, BTK antibody, Bruton's tyrosine kinase antibody, Bruton agammaglobulinemia tyrosine kinase antibody, agammaglobulinaemia tyrosine kinase antibody, AGMX1 antibody, AT antibody, atk antibody, B-cell progenitor kinase antibody, BOS_25575 antibody, bpk antibody, Brutons tyrosine kinase antibody, bruton tyrosine kinase antibody, dominant-negative kinase-deficient Brutons tyrosine kinase antibody, imd1 antibody, kinase EMB antibody, psctk1 antibody, RCJMB04_6h8 antibody, RP1-164F3.2 antibody, RP23-91G19.5 antibody, tyrosine-protein kinase BTK antibody, Tyrosine-protein kinase BTK (Brutons tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB) antibody, tyrosine-protein kinase BTK isoform (lacking exon 14) antibody, xid antibody, XLA antibody, X-linked immune deficiency antibody |
|---|---|
| Cross Reactivity | Human |
| Applications | ELISA, IHC-P, WB |
| Immunogen | Brutons tyrosine kinase antibody was raised in Mouse using a recombinant human protein purified from E.coli (His/ABD-Btk) as the immunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 1A1 |
| Isotype | IgG1 kappa |
| Method of Purification | Brutons tyrosine kinase antibody was purified by ammonium sulfate precipitation |
| Form & Buffer | Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
STORAGE & SAFETY:
| Storage | Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles |
|---|
Usage Assay Information:
| Usage Recommendations | WB: 1:5000 |
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GENERAL INFORMATION:
| Biological Significance | Btk (Brutons tyrosine kinase) is a member of the Tec family of protein tyrosine kinases (PTKs) and plays a modulatory role in many cellular processes, such as proliferation, development, differentiation, survival, and apoptosis. The Tec kinases are the second largest family of non-receptor tyrosine kinases and include Tec, Btk, Bmx, Itk, and TXK/Rlk. Mutations of Btk gene cause a primary immunodeficiency disease in humans, X-linked agammaglobulinemia (XLA) which is characterized by a lack of circulating B lymphocytes and an absence of immunoglobulins as a result of defects in B cell maturation and function. Btk is found in all hematopoietic cells, with the exception of T lymphocytes and plasma cells. Btk contains amino-terminal PH (pleckstrin homology) domain which binds phosphatidylinositol (3,4,5)-trisphosphate (PIP3) helping membrane translocation upon PI3 kinase activation. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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