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Fitzgerald/Complement C4 beta chain antibody/10R-8481/100 ul
Fitzgerald/Complement C4 beta chain antibody/10R-8481/100 ul
商品编号：
10R-8481-100ul
品牌：
fitzgerald-fii
市场价：
¥5900.00
美元价：
4425.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal Complement C4 beta chain antibody, Anti-Complement C4 beta chain antibody, C4B antibody, complement component 4B (Chido blood group) antibody, basic complement C4 antibody, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3 antibody, C4 antibody, C4-2 antibody, C4B1 antibody, C4B12 antibody, C4B2 antibody, C4B3 antibody, C4B5 antibody, C4BD antibody, C4F antibody, C4l antibody, CH antibody, Chido form of C4 antibody, CO4 antibody, complement C4-A-like antibody, complement C4-B antibody, complement C4B1a antibody, complement C4-like protein antibody, complement component 4B (Childo blood group) antibody, complement component 4 antibody, gene 2 antibody, complement component 4 (within H-2S) antibody, CPAMD3 antibody, DADB-112B14.11-001 antibody, Orla C4 antibody, PANDA_019918 antibody, Ss antibody |
|---|---|
| Cross Reactivity | Human |
| Applications | ELISA, IP, WB |
| Immunogen | Complement C4 beta chain antibody was raised in Mouse using a protein purified from Human plasma as the immunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 52H10 |
| Isotype | IgG1 kappa |
| Method of Purification | Complement C4 beta chain antibody was purified by ammonium sulfate precipitation |
| Form & Buffer | Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
STORAGE & SAFETY:
| Storage | Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles |
|---|
Usage Assay Information:
| Usage Recommendations | WB: 1:2000, IP: 1 ul |
|---|
GENERAL INFORMATION:
| Biological Significance | Complement component C4 is an essential component of humoral immune response. In its activated form, C4b becomes a subunit of the C3 convertase, which is an enzymatic complex that activates C3 of the classical and lectin complement activation pathways. The classical pathway is initiated by the activation of the C1-complex (C1q, C1r and C1s) by C1q's binding to antibody-antigen. The C1-complex now binds to and splits C2 and C4 producing C2a and C4b. C4b and C2a bind to form C3-convertase. Production of C3-convertase leads to cleavage of C3 into C3a and C3b and C3b joins with the C3 convertase to make C5 convertase. Human C4 is the most polymorphic protein of the complement system. Complement C4 exists as two isotypes, C4A (acidic) and C4B (basic). Although the sequence identity is very high, they have different hemolytic activities, covalent affinities to antigens and immune complexes, and serological reactivities. Each C4 contains beta chain, alpha chain, C4a anaphyltoxin, C4b, and gamma chain. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
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