Fitzgerald/Complement Factor B antibody/10R-8452/100 ul
商品编号：
10R-8452-100ul
品牌：
fitzgerald-fii
市场价：
¥5900.00
美元价：
4425.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal Complement Factor B antibody, Anti-Complement Factor B antibody, CFB antibody, complement Factor B antibody, ahus4 antibody, alternative-complement pathway C3/C5 convertase antibody, B antibody, BF antibody, Bf-1 antibody, B-Factor antibody, properdin antibody, Bf B antibody, bfb-A antibody, bfd antibody, Brre-Bf antibody, C2 antibody, C3/C5 convertase antibody, C3 proaccelerator antibody, C3 proactivator antibody, CFAB antibody, complement component 2 (within H-2S) antibody, complement component Factor B antibody, complement Factor Bf-1 antibody, Da1-24 antibody, DADB-122G4.5 antibody, EC-VMFB antibody, Factor B antibody, Fb antibody, FBI12 antibody, fbl12 antibody, gbg antibody, glycine-rich beta glycoprotein antibody, glycine-rich beta-glycoprotein antibody, H2-Bf antibody, histocompatibility 2 antibody, complement component Factor B antibody, pbf2 antibody, properdin antibody, properdin Factor B antibody, RP24-317H19.4 antibody, SBAB-707F1.11-001 antibody |
|---|---|
| Cross Reactivity | Human |
| Applications | ELISA, WB |
| Immunogen | Complement Factor B antibody was raised in Mouse using a protein purified from Human plasma as the immunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 28A3 |
| Isotype | IgG1 kappa |
| Method of Purification | Complement Factor B antibody was purified by ammonium sulfate precipitation |
| Form & Buffer | Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
STORAGE & SAFETY:
| Storage | Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles |
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Usage Assay Information:
| Usage Recommendations | WB: 1:1000 |
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GENERAL INFORMATION:
| Biological Significance | Complement Factor B, a 93 kDa glycoprotein, is a component of the alternative complement pathway. Complement Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement Factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. The alternative pathway is associated with inflammation, immunologic regulation, and bacterial cytotoxicity. In addition to its roles in the activation of the alternative pathway and enhancing bacterial phagocytosis by macrophages, Complement Factor B may also play a role in B cell proliferation, monocyte cytotoxicity, macrophage spreading, immunosuppression, and apoptosis. Complement Factor B has been shown to be involved in many diseases such as septic shock, stroke, systemic lupus erythematosus, Alzheimer?s disease, and multiple sclerosis. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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