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当前位置: 首页 > 产品中心 > Functional_antibody > Fitzgerald/Complement Factor C8 beta propeptide antibody/10R-8464/100 ul
商品详细Fitzgerald/Complement Factor C8 beta propeptide antibody/10R-8464/100 ul
Fitzgerald/Complement Factor C8 beta propeptide antibody/10R-8464/100 ul
Fitzgerald/Complement Factor C8 beta propeptide antibody/10R-8464/100 ul
商品编号: 10R-8464-100ul
品牌: fitzgerald-fii
市场价: ¥5900.00
美元价: 4425.00
产地: 美国(厂家直采)
公司:
产品分类: 功能性抗体
公司分类: Functional_antibody
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

OVERVIEW:

Synonyms Monoclonal Complement Factor C8 beta propeptide antibody, Anti-Complement Factor C8 beta propeptide antibody, C8B antibody, complement component 8 antibody, beta polypeptide antibody, BOS_3527 antibody, complement component 8 antibody, beta subunit antibody, complement component 8 subunit beta antibody, complement component C8 beta chain antibody, complement component C8 beta subunit antibody, RP23-413I9.1 antibody
Cross Reactivity Human
Applications ELISA, IP, WB
Immunogen Complement Factor C8 beta propeptide antibody was raised in Mouse using a protein purified from Human plasma as the immunogen

SPECIFICATIONS:

Host Mouse
Clone 14A10
Isotype IgG1 kappa
Method of Purification Complement Factor C8 beta propeptide antibody was purified by ammonium sulfate precipitation
Form & Buffer Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol

STORAGE & SAFETY:

Storage Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles

Usage Assay Information:

Usage Recommendations WB: 1:2000, IP: 1 ul

GENERAL INFORMATION:

Biological Significance The complement system is a part of the larger immune system and three biochemical pathways are present: the classical complement pathway, the alternative pathway, and the mannose-binding lectin pathway. Human complement Factor C8 is one of five components (C5b, C6, C7, C8, and C9) that interact to form the cytolytic membrane attack complex (MAC) which is the cytolytic end product of the complement cascade. MAC is typically formed on the surface of intruding pathogenic bacterial as a result of the activation of the complement system, and it is one of the ultimate weapons of the immune system. C8 is composed of an alpha (64 kDa), beta (64 kDa), and gamma (22 kDa) subunit. Within C8, the subunits are arranged as a disulfide-linked C8 alpha-gamma heterodimer that is noncovalently associated with C8 beta. During MAC formation, C8 alpha mediates binding and self-polymerization of C9 to form a pore-like structure on the membrane of target cells.
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。