Fitzgerald/Gelsolin antibody/10R-8459/100 ul
商品编号：
10R-8459-100ul
品牌：
fitzgerald-fii
市场价：
¥6720.00
美元价：
5040.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal Gelsolin antibody, Anti-Gelsolin antibody, GSN antibody, gelsolin antibody, actin-depolymerizing factor antibody, ADF antibody, AGEL antibody, brevin antibody, gelsolin (amyloidosis antibody, Finnish type) antibody, homogenin antibody, RP11-477J21.1 antibody, RP23-186B18.2 antibody, scin antibody, scinderin antibody |
|---|---|
| Cross Reactivity | Human |
| Applications | IP, WB |
| Immunogen | Gelsolin antibody was raised in Mouse using a protein purified from Human plasma as the immunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 35B2 |
| Isotype | IgG1 kappa |
| Method of Purification | Gelsolin antibody was purified by ammonium sulfate precipitation |
| Form & Buffer | Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
STORAGE & SAFETY:
| Storage | Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles |
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Usage Assay Information:
| Usage Recommendations | WB: 1:2000, IP: 0.5 ul |
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GENERAL INFORMATION:
| Biological Significance | Gelsolin superfamily proteins control actin organization by severing filaments, capping filament ends and nucleating actin assembly. Gelsolin, a protein of 82?84 kDa, is the founding member of this family, which now contains at least another six members: villin, adseverin, capG, advillin, supervillin and flightless I. Gelsolin exists as a cytoplasmic as well as a plasma isoform, and can bind, sever and cap actin filaments. Plasma gelsolin level decreases dramatically as a result of major trauma and reinfusion of gelsolin can protect against lung damage associated with major burn injury and other types of insults. Recent study in Fas antibody-induced liver failure suggests that gelsolin exerts an overall anti-apoptotic effect in vivo. Gelsolin, a marker of motility, could be applied as a biomarker in assessing tumor prognosis. Tumor-associated processes such as invasion and metastasis are known to be critically dependent on dynamic alterations in the organization of the actin cytoskeleton. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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