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Fitzgerald/Hairy and Enhancer of Split 1 antibody/10R-8467/100 ul
Fitzgerald/Hairy and Enhancer of Split 1 antibody/10R-8467/100 ul
商品编号：
10R-8467-100ul
品牌：
fitzgerald-fii
市场价：
¥5900.00
美元价：
4425.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal Hairy and Enhancer of Split 1 antibody, Anti-Hairy and Enhancer of Split 1 antibody, Hes1 Hairy and enhancer of split 1 Hairy Enhancer of Split 1 Hairy Homolog Hairy like HHL HL HRY Transcription factor HES 1 antibody, Q8IXV0 antibody |
|---|---|
| Cross Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IP, WB |
| Immunogen | Hairy and Enhancer of Split 1 antibody was raised in Mouse using a His-tagged recombinant human Hes1 protein purified from E.coli as the immunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 7H11 |
| Isotype | IgG2b kappa |
| Method of Purification | Hairy and Enhancer of Split 1 antibody was purified by ammonium sulfate precipitation |
| Form & Buffer | Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
STORAGE & SAFETY:
| Storage | Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles |
|---|
Usage Assay Information:
| Usage Recommendations | WB: 1:500-1000, IP: 1 ul |
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GENERAL INFORMATION:
| Biological Significance | The Notch signaling pathway is important for cell-cell communication, which involve gene regulation mechanisms that control multiple cell differentiation processes during embryonic and adult life. It critically influences cell proliferation, differentiation, and apoptosis in metazoans. The hairy and enhancer of split (HES) family is a basic helix-loop-helix (bHLH) type trancriptional repressor and acts as Notch effectors by negatively regulating expression of downstream target genes such as tissue-specific transcription factors. HES-1 is an upstream negative regulator of REST expression. Silencing of the transcriptional repressor REST is required for terminal differentiation of neuronal and beta-cells. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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