菲茨杰拉德/人IgM抗体/10R-8447/100微升
商品编号:
10R-8447-100ul
品牌:
fitzgerald-fii
市场价:
¥6720.00
美元价:
5040.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
OVERVIEW:
Synonyms | Monoclonal Human IgM antibody, Anti-Human IgM antibody, Human IgM antibody, Constant region of heavy chain of IgM antibody, Ig mu chain C region antibody, IGHM antibody, Immunoglobin heavy constant mu antibody, Immunoglobulin mu antibody, Immunoglobulin mu chain antibody, Imunoglobulin heavy chain antibody, MU antibody, VH antibody, P01871 antibody |
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Cross Reactivity | Human |
Applications | ELISA, IHC-P, IP, WB |
Immunogen | Human IgM antibody was raised in Mouse using a protein purified from Human plasma as the immunogen |
SPECIFICATIONS:
Host | Mouse |
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Clone | 13A11 |
Isotype | IgG1 lambda |
Method of Purification | Human IgM antibody was purified by ammonium sulfate precipitation |
Form & Buffer | Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
STORAGE & SAFETY:
Storage | Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles |
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Usage Assay Information:
Usage Recommendations | WB: 1:2000, IP: 0.5 ul |
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GENERAL INFORMATION:
Biological Significance | Immunoglobulin M (IgM) forms polymers where multiple immunoglobulins are covalently linked together with disulfide bonds, normally as a pentamer and the J chain is attached to most pentamers. It has a large molecular mass of approximately 900 kD. Due to its polymeric nature, IgM possesses high avidity, and is particularly effective at complement activation. It is sometimes called a "natural antibody", but it is likely that the antibodies arise due to sensitization in the very young to antigens that are naturally occurring in nature. IgM is the first immunoglobulin expressed by mature B cells. IgM antibodies appear early in the course of an infection and usually do not reappear after further exposure. IgM antibodies do not pass across the human placenta. These two biological properties of IgM make it useful in the diagnosis of infectious diseases. Demonstrating IgM antibodies in patients serum indicates recent or in serum from a neonate intrauterine infection such as congenital rubella. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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