Fitzgerald/MEK2 antibody/10R-8476/100 ul
商品编号：
10R-8476-100ul
品牌：
fitzgerald-fii
市场价：
¥6720.00
美元价：
5040.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal MEK2 antibody, Anti-MEK2 antibody, MAP2K2 antibody, mitogen-activated protein kinase kinase 2 antibody, BOS_7688 antibody, dual specificity mitogen activated protein kinase kinase 2 antibody, dual specificity mitogen-activated protein kinase kinase 2 antibody, ERK activator kinase 2 antibody, MAPK/ERK kinase 2 antibody, MAP kinase/Erk kinase antibody, MAP kinase kinase 2 antibody, MAPKK2 antibody, MAPKK 2 antibody, MEK2 antibody, MEK 2 antibody, mitogen activated protein kinase kinase 2 antibody, mitogen-activated protein kinase kinase 2 antibody, p45 antibody, mitogen-activated protein kinase kinase type 2 antibody, MK2 antibody, MKK2 antibody, PRKMK2 antibody, protein kinase antibody, mitogen activated antibody, kinase 2 antibody, p45 antibody |
|---|---|
| Cross Reactivity | Human |
| Applications | IP, WB |
| Immunogen | MEK2 antibody was raised in Mouse using a recombinant human protein purified from E.coli (His-MEK2) as the immunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 1A1 |
| Isotype | IgG1 kappa |
| Method of Purification | MEK2 antibody was purified by ammonium sulfate precipitation |
| Form & Buffer | Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
STORAGE & SAFETY:
| Storage | Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles |
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Usage Assay Information:
| Usage Recommendations | WB: 1: 2000, IP: 2 ul |
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GENERAL INFORMATION:
| Biological Significance | The ERK (extracellular-signal regulated kinase) cascade is a central MAPK pathway which contains Ras as a G protein, Raf as a MAPKKK, MEK1 (MAPK/ERK kinase1) and MEK2 (MAPK/ERK kinase2) as MAPKK, and ERKs as MAPK. MEK1 and MEK2 are 80% identical to each other, and are essentially identical in most of their kinase domain. MEK1 and MEK2 phosphorylate ERKs equally well, both in vivo and in vitro. MEK1 (45 kDa) and MEK2 (46 kDa) are composed of a catalytic kinase domain, which is surrounded by a regulatory N-terminal domain ( 80 amino acids) and a shorter C-terminal region ( 30 amino acids). Unlike the kinase domains, the N-termini and the characteristic Pro-rich inserts are quite divergent between the two MEKs (40% identity). MEKs are activated by phosphorylation of two Ser residues in their activation loop (Ser218 and Ser222 in MEK1) located within a Ser?Xaa?Ala?Xaa?Ser/Thr motif, typical to all MAPKKs. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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