Fitzgerald/mTOR antibody/10R-8644/100 ul
商品编号：
10R-8644-100ul
品牌：
fitzgerald-fii
市场价：
¥5900.00
美元价：
4425.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal mTOR antibody, Anti-mTOR antibody, MTOR antibody, mechanistic target of rapamycin (serine/threonine kinase) antibody, angiopoietin-like factor CDT6 antibody, BOS_15830 antibody, Bx34 antibody, CG8274-PA antibody, CH211-119D14.6 antibody, Dmel_CG8274 antibody, fc22h08 antibody, FK506 binding protein 12-rapamycin associated protein 1 antibody, FK506 binding protein 12-rapamycin associated protein 2 antibody, FK506-binding protein 12-rapamycin complex-associated protein 1 antibody, FKBP12-rapamycin complex-associated protein antibody, FKBP12-rapamycin complex-associated protein 1 antibody, FKBP-rapamycin associated protein antibody, FKBP-rapamycin associated protein (FRAP) antibody, FKBP-rapamycin-associated protein FRAP antibody, flat antibody, FRAP antibody, frap1 antibody, FRAP2 antibody, lethal (2) k03905 antibody, mammalian target of rapamycin antibody, Megator antibody, Mtor-PA antibody, RAFT1 antibody, rapamycin and FKBP12 target 1 antibody, rapamycin and FKBP12 target-1 protein antibody, rapamycin associated protein FRAP2 antibody, rapamycin target protein 1 antibody, RAPT1 antibody, RP23-423L9.1 antibody, serine/threonine-protein kinase mTOR antibody, serine/threonine-protein kinase mTOR-like antibody, target of rapamycin antibody, tor antibody, Tpr antibody |
|---|---|
| Cross Reactivity | Human |
| Applications | WB |
| Immunogen | mTOR antibody was raised in Mouse using a recombinant human protein purified from E.coli (His-mTOR) as the immunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 53E11 |
| Isotype | IgG1 kappa |
| Form & Buffer | Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
STORAGE & SAFETY:
| Storage | Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles |
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Usage Assay Information:
| Usage Recommendations | WB: 1:2000 |
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GENERAL INFORMATION:
| Biological Significance | Mammalian target of rapamycin (mTOR) is a serine/threonine kinase involved in diverse cellular processes, including protein translation, mRNA turnover, and protein stability, mediates, at least in part, some of the biological actions of Akt. As a Kinase subunit of both mTORC1 (complex1) and mTORC2 (complex2), mTOR regulates cell growth and survival in response to nutrient and hormonal signals. mTORC1 is activated in response to growth factors or amino-acids. Activated mTORC1 up-regulates protein synthesis by phosphorylating key regulators of mRNA translation and ribosome synthesis. mTORC1 phosphorylates EIF4EBP1 and releases it from inhibiting the elongation initiation factor 4E (eiF4E). mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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