Fitzgerald/Peroxiredoxin SO3 antibody/10R-8413/100 ul
商品编号：
10R-8413-100ul
品牌：
fitzgerald-fii
市场价：
¥5900.00
美元价：
4425.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal Peroxiredoxin SO3 antibody, Anti-Peroxiredoxin SO3 antibody, PRDX1 antibody, peroxiredoxin 1 antibody, BOS_3608 antibody, CH211-284B7.7 antibody, EGK_00700 antibody, Hbp23 antibody, heme-binding 23 kDa protein antibody, macrophage 23 kDa stress protein antibody, macrophage 23kDa stress protein antibody, macrophage 23 Kd stress protein antibody, macrophase stress protein 22kDa antibody, macrophase stress protein 23 kd antibody, MSP23 antibody, natural killer cell-enhancing factor A antibody, natural killer-enhancing factor A antibody, nkefa antibody, NKEF-A antibody, OSF3 antibody, OSF-3 antibody, osteoblast specific factor 3 antibody, osteoblast-specific factor 3 antibody, PAG antibody, paga antibody, pagb antibody, Peroxiredoxin-1 antibody, PrdxI antibody, proliferation-associated gene A antibody, proliferation-associated gene protein antibody, prx1 antibody, prx-1 antibody, PrxI antibody, RP23-177C18.2 antibody, Tdpx2 antibody, TDX2 antibody, thioredoxin dependent peroxide reductase 2 antibody, thioredoxin-dependent peroxide reductase 2 antibody, Thioredoxin peroxidase 2 antibody, thioredoxin peroxidase II antibody, TPX-2 antibody, TPxA antibody, Trx dependent peroxide reductase 2 antibody |
|---|---|
| Cross Reactivity | Human |
| Applications | WB |
| Immunogen | Peroxiredoxin SO3 antibody was raised in Mouse using a sulfonylated peptide(KLH coupled) corresponding to the active site sequence common to mammalian Prx I to IV as the immunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 10A1 |
| Isotype | IgG1 kappa |
| Method of Purification | Peroxiredoxin SO3 antibody was purified by ammonium sulfate precipitation |
| Form & Buffer | Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
STORAGE & SAFETY:
| Storage | Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles |
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Usage Assay Information:
| Usage Recommendations | WB: 1:100-500 |
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GENERAL INFORMATION:
| Biological Significance | Peroxiredoxin, an antioxidant enzyme detoxifying reactive oxygen species and has a cysteine at their active site. Prx enzymes modulate various receptor signaling pathways and protect cells from oxidatively induced death. Prx I to IV have two conserved Cys residues corresponding to Cys51 and Cys172 of mammalian Prx I. The active site cysteine (Cys51) is oxidized to cysteine sulfenic acid (Cys51-SOH) when a peroxide is reduced. Because Cys51-SOH is unstable, it forms a disulfide with Cys172-SH which comes from other subunit of the homodimer. The disulfide is then reduced back to the Prx active thiol form by the thioredoxin-thioredoxin reductase system. However, the formation of the disulfide is a slow process. Thus under oxidative stress condition, the sulfenic intermediate (Cys51-SOH) can be easily overoxidized to cysteine sulfinic acid (Cys-SO2H) or cysteine sulfonic acid (Cys-SO3H) before it is able to form a disulfide. Recent studies suggest that overoxidized Prx can be reduced back to the active form during recovery after oxidative stress. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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