菲茨杰拉德/PLK1抗体/10R-8477/100微升
商品编号：
10R-8477-100ul
品牌：
fitzgerald-fii
市场价：
¥6720.00
美元价：
5040.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal PLK1 antibody, Anti-PLK1 antibody, PLK1 antibody, polo-like kinase 1 antibody, BOS_22765 antibody, cell cycle regulated protein kinase antibody, EGK_12605 antibody, ik:tdsubc_2d1 antibody, NV_30481 antibody, NV50027 antibody, plk antibody, PLK-1 antibody, Plx1 antibody, polo (Drosophia)-like kinase antibody, polo like kinase antibody, polo-like kinase 1 (Drosophila) antibody, polo-like kinase homolog antibody, polo-like protein kinase antibody, RCJMB04_20p15 antibody, serine/threonine-protein kinase 13 antibody, serine/threonine-protein kinase PLK1 antibody, STPK13 antibody, xx:tdsubc_2d1 antibody |
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| Cross Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IP, WB |
| Immunogen | PLK1 antibody was raised in Mouse using a recombinant human protein purified from E.coli (GST/His-Plk1) as the immunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 18D4 |
| Isotype | IgG1 kappa |
| Method of Purification | PLK1 antibody was purified by ammonium sulfate precipitation |
| Form & Buffer | Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
STORAGE & SAFETY:
| Storage | Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles |
|---|
Usage Assay Information:
| Usage Recommendations | WB: 1:1000, IP: 1 ul |
|---|
GENERAL INFORMATION:
| Biological Significance | Polo-like kinases (Plks) are important regulators of the cell cycle. Plk1, the most studied Plk, has been implicated in regulating centrosome maturation, mitotic entry, sister chromatid cohesion, the anaphase-promoting complex/cyclosome (APC/C), and cytokinesis. Sister chromatid separation and the subsequent formation of two genetically identical daughter cells depend on the symmetrical attachment of all chromosomes to the mitotic spindle, a process called chromosome biorientation. Several mitosis-specific protein kinases have been implicated in bipolar spindle assembly and chromosome biorientation. For example, Cdk1 (cyclin-dependent kinase 1) is known to phosphorylate Eg5, a kinesin that is required for the migration of centrosomes and is thus needed for the formation of bipolar spindles.At the onset of mitosis, Plks contribute to the activation of Cdk1-cyclinB, and they are also required for the inactivation of Cdk1 and exit from mitosis. Plks are important regulators of the APC/C, a key component of the ubiquitin-dependent proteolytic degradation pathway. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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