
菲茨杰拉德/对氧磷酶1抗体/10R-8414/100微升
商品编号:
10R-8414-100ul
品牌:
fitzgerald-fii
市场价:
¥5900.00
美元价:
4425.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
OVERVIEW:
Synonyms | Monoclonal Paraoxonase 1 antibody, Anti-Paraoxonase 1 antibody, PON1 antibody, paraoxonase 1 antibody, A-esterase 1 antibody, aromatic esterase 1 antibody, arylesterase B-type antibody, BOS_4019 antibody, EGK_13925 antibody, ESA antibody, esterase A antibody, K-45 antibody, MVCD5 antibody, paraoxonase B-type antibody, Pon antibody, PON 1 antibody, serum aryldiakylphosphatase antibody, serum aryldialkylphosphatase 1 antibody, serum paraoxonase antibody, serum paraoxonase/arylesterase 1 antibody |
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Cross Reactivity | Human, Mouse, Rat |
Applications | WB |
Immunogen | Paraoxonase 1 antibody was raised in Mouse using a His-tagged recombinant human PON1 protein purified E.coli as the immunogen |
SPECIFICATIONS:
Host | Mouse |
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Clone | 17A12 |
Isotype | IgG1 kappa |
Method of Purification | Paraoxonase 1 antibody was purified by ammonium sulfate precipitation |
Form & Buffer | Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
STORAGE & SAFETY:
Storage | Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles |
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Usage Assay Information:
Usage Recommendations | WB: 1:500 |
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GENERAL INFORMATION:
Biological Significance | The paraoxonase (PON) gene-family in humans has three members, PON1, PON2, and PON3, aligned next to each other on the long arm of chromosome 7q21.3-22.1. PON1 of these is synthesized primarily in the liver and a portion is secreted into the plasma, where it is associated with high density lipoproteins (HDL). And It hydrolyzes the active metabolites of several other organophosphorus insecticides (e.g., chlorpyrifos oxon, diazoxon), as well as nerve agents such as sarin, soman and VX (lethal nerve agent). The PON1 polymorphism may be responsible for neurodegeneration and considered to be an independent risk factor for Parkinson?s disease. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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