Fitzgerald/Prothrombin precursor antibody/10R-8454/100 ul
商品编号：
10R-8454-100ul
品牌：
fitzgerald-fii
市场价：
¥5900.00
美元价：
4425.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal Prothrombin precursor antibody, Anti-Prothrombin precursor antibody, F2 antibody, coagulation factor II (thrombin) antibody, Cf2 antibody, Cf-2 antibody, coagulation factor 2 antibody, coagulation factor 2 (thrombin) antibody, coagulation factor II antibody, F2_BB antibody, FII antibody, Prothrombin antibody, prothrombin B-chain antibody, prothrombin precursor antibody, PT antibody, RP23-176N9.4 antibody, RPRGL2 antibody, serine protease antibody, silk fibroin 2 antibody, THPH1 antibody, thrombin antibody, thrombin B chain variant 1 antibody, vitamin K dependent serine protease antibody |
|---|---|
| Cross Reactivity | Human |
| Applications | ELISA, WB |
| Immunogen | Prothrombin precursor antibody was raised in Mouse using a protein purified from Human plasma as the immunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 28H5 |
| Isotype | IgG2b kappa |
| Method of Purification | Prothrombin precursor antibody was purified by ammonium sulfate precipitation |
| Form & Buffer | Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
STORAGE & SAFETY:
| Storage | Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles |
|---|
Usage Assay Information:
| Usage Recommendations | WB: 1:1000 |
|---|
GENERAL INFORMATION:
| Biological Significance | Prothrombin precursor is synthesized in liver as a precursor of prothrombin containing a signal sequence and a propeptide domain at the N-terminus. Before its secretion into plasma, this precursor undergoes several posttranslational modifications, including removal of signal sequence and propeptide domains, glycosylation, and gamma-glutamyl-carboxylation reaction. Prothrombin, cleaved by the prothrombinase enzyme complex that consists of serine protease factor Xa, cofactor Va, phospholipids and calcium, is converted to thrombin which converts fibrinogen into fibrin which in turn strengthens a protective clot. Activation of prothrombin is crucial in physiological and pathological coagulation. Various rare diseases involving prothrombin (e.g. hypoprothrombinemia) have been described. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
联络我们
