Fitzgerald/Shc1 antibody/10R-8484/100 ul
商品编号:
10R-8484-100ul
品牌:
fitzgerald-fii
市场价:
¥5900.00
美元价:
4425.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
OVERVIEW:
Synonyms | Monoclonal Shc1 antibody, Anti-Shc1 antibody, SHC1 antibody, SHC (Src homology 2 domain containing) transforming protein 1 antibody, adaptor protein SHC antibody, BOS_2793 antibody, p60Shc antibody, p66 antibody, p66shc antibody, RP11-307C12.1 antibody, SH2 domain protein C1 antibody, shc antibody, ShcA antibody, SHC (Src homology 2 domain-containing) transforming protein 1 antibody, SHC-transforming protein 1 antibody, SHC-transforming protein 3 antibody, SHC-transforming protein A antibody, src homology 2 domain-containing transforming protein C1 antibody, src homology 2 domain-containing-transforming protein C1 antibody, src homology collagen antibody |
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Cross Reactivity | Human, Mouse, Rat |
Applications | ELISA, IP, WB |
Immunogen | Shc1 antibody was raised in Mouse using a recombinant human protein purified from E.coli (His/ABD-Shc1) as the immunogen |
SPECIFICATIONS:
Host | Mouse |
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Clone | 47F4 |
Isotype | IgG1 kappa |
Method of Purification | Shc1 antibody was purified by ammonium sulfate precipitation |
Form & Buffer | Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
STORAGE & SAFETY:
Storage | Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles |
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Usage Assay Information:
Usage Recommendations | WB: 1: 5000, IP: 1 ul |
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GENERAL INFORMATION:
Biological Significance | Shc1 is a prototype adapter protein that is expressed from the earliest stages of T-cell development. Shc becomes rapidly tyrosine phosphorylated after T-cell receptor (TCR) engagement. Three shc genes have been identified in mammals and their gene products have been referred to as ShcA, ShcB and ShcC. ShcA is ubiquitously expressed, while shcB and ShcC expression appear limited to neuronal cells. ShcA is expressed as three isoforms of about 46, 52 and 66 kDa. Shc is composed of an N-terminal PTB, a central collagen-homology (CH) domain and a C-terminal SH2 domain. The 66 kDa isoform of ShcA is expressed in most cells except in the hematopoietic lineage and contains an additional amino-terminal CH-like region. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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