Fitzgerald/SHP2 antibody/10R-8469/100 ul
商品编号：
10R-8469-100ul
品牌：
fitzgerald-fii
市场价：
¥5900.00
美元价：
4425.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal SHP2 antibody, Anti-SHP2 antibody, PTPN11 antibody, protein tyrosine phosphatase antibody, non-receptor type 11 antibody, BOS_16688 antibody, BPTP3 antibody, CFC antibody, cSH-PTP2 antibody, encodes catalytic domain antibody, non-receptor type protein tyrosine phosphatase SHP2 antibody, NS1 antibody, null antibody, phosphotyrosyl-protein phosphatase antibody, protein-tyrosine phosphatase 1D antibody, protein-tyrosine phosphatase 2C antibody, protein tyrosine phosphatase antibody, non-receptor type 11 (Noonan syndrome 1) antibody, protein tyrosine phosphatase SH-PTP2 antibody, protein-tyrosine phosphatase SYP antibody, PTP1D antibody, PTP-1D antibody, ptp-2 antibody, PTP2C antibody, PTP-2C antibody, SAP-2 antibody, SH2 domain-containing protein tyrosine phosphatase-2 antibody, Shp2 antibody, SHP-2 antibody, SH-PTP2 antibody, SH-PTP2 protein tyrosine phosphatase non-receptor type 11 antibody, SH-PTP2 protein tyrosine phosphatase antibody, non-receptor type 11 antibody, SH-PTP3 antibody, SYP antibody, tyrosine-protein phosphatase non-receptor type 11 antibody |
|---|---|
| Cross Reactivity | Human, Mouse, Rat |
| Applications | IP, WB |
| Immunogen | SHP2 antibody was raised in Mouse using a recombinant human GST-SHP2 protein purified from E.coli as the immunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | 5F2 |
| Isotype | IgG1 kappa |
| Method of Purification | SHP2 antibody was purified by ammonium sulfate precipitation |
| Form & Buffer | Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
STORAGE & SAFETY:
| Storage | Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles |
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Usage Assay Information:
| Usage Recommendations | WB: 1:2000, IP: 1 ul |
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GENERAL INFORMATION:
| Biological Significance | SHP2 is a tyrosine phosphatase containing two tandem SH2 (src homology 2) domains. Protein tyrosine phosphatases (PTPs) are a group of enzymes that remove phosphate groups from phosphorylated tyrosine residues on proteins. Together with tyrosine kinases, PTPs regulate the phosphorylation state of many important signaling molecules. SHP1 and SHP2 represent a subfamily of non-transmembrane PTPs that contain two SH2 domains followed by a PTP domain. Tyrosine phosphorylation of SHP2 is required for normal ERK activation in response to some growth factors. In the inactive state, the N-terminal SH2 domain binds the PTP domain and blocks access of potential substrates to the active site. This auto-inhibition is relieved by the binding of phosphopeptides to SH2 domain, resulting in activation of phostphatase activity. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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