Fitzgerald/SOS1 antibody/10R-8598/100 ul
商品编号：
10R-8598-100ul
品牌：
fitzgerald-fii
市场价：
¥6720.00
美元价：
5040.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal SOS1 antibody, Anti-SOS1 antibody, SOS1 antibody, son of sevenless homolog 1 (Drosophila) antibody, 9630010N06 antibody, BOS_11522 antibody, fj59e07 antibody, GF1 antibody, GGF1 antibody, GINGF antibody, gingival fibromatosis antibody, hereditary antibody, 1 antibody, guanine nucleotide exchange factor antibody, guanine nucleotide releasing factor antibody, HGF antibody, NS4 antibody, PANDA_013349 antibody, ras guanine exchange factor antibody, son-of-sevenless 1 antibody, son of sevenless homolog antibody, Son of sevenless homolog 1 antibody, SOS-1 antibody |
|---|---|
| Cross Reactivity | Human, Mouse, Rat |
| Applications | ELISA, WB |
| Immunogen | SOS1 antibody was raised in Mouse using a recombinant human protein purified from E.coli (His/ABD-SOS1) as the immunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | AF3F11 |
| Isotype | IgG1 kappa |
| Method of Purification | SOS1 antibody was purified by ammonium sulfate precipitation |
| Form & Buffer | Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
STORAGE & SAFETY:
| Storage | Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles |
|---|
Usage Assay Information:
| Usage Recommendations | WB: 1:1000 |
|---|
GENERAL INFORMATION:
| Biological Significance | Son of sevenless (SOS) is a guanine nucleotide exchange factor that activates Ras in response to growth factor stimulation. Sos1, and itsclosely related Sos2 paralog, are comprised of an N-terminal histone-binding domain, a Rac GEF catalytic (DH) domain juxtaposed with a PH domain, a Ras exchanger motif (REM) domain, a Ras GEF catalytic domain, and a C-terminal proline-rich region. Sos1 catalyzes the GDP-GTP exchange within the membrane-bound GTPase Ras andthereby switches on a key signaling circuit that involves the activation of MAPK cascade central to cellular proliferation, survival and differentiation. Growth factor stimulation rapidly induces the phosphorylation of Sos on multiple serine and threonine sites. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
联络我们
