Fitzgerald/TCPTP antibody/10R-8623/100 ul
商品编号：
10R-8623-100ul
品牌：
fitzgerald-fii
市场价：
¥6720.00
美元价：
5040.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal TCPTP antibody, Anti-TCPTP antibody, PTPN2 antibody, protein tyrosine phosphatase antibody, non-receptor type 2 antibody, BOS_22287 antibody, MPTP antibody, phosphoprotein phosphatase antibody, protein-tyrosine phosphatase PTP-2 antibody, protein-tyrosine phosphatase PTP-S antibody, ptn2 antibody, Ptpt antibody, T cell protein-tyrosine phosphatase antibody, T-cell protein tyrosine phosphatase antibody, TCELLPTP antibody, TCPTP antibody, TC-PTP antibody, tyrosine-protein phosphatase non-receptor type 2 antibody |
|---|---|
| Cross Reactivity | Human |
| Applications | ELISA, WB |
| Immunogen | TCPTP antibody was raised in Mouse using a recombinant human protein purified from E.coli as the immunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | T25-AF3B7 |
| Isotype | IgG2b kappa |
| Method of Purification | TCPTP antibody was purified by ammonium sulfate precipitation |
| Form & Buffer | Supplied in liquid form in HEPES buffer with 0.15M NaCl, 0.01% BSA, 0.03% sodium azide, and 50% glycerol |
STORAGE & SAFETY:
| Storage | Aliquot and store for 1 year at -20 deg C, avoid freeze/thaw cycles |
|---|
Usage Assay Information:
| Usage Recommendations | WB: 1:2000 |
|---|
GENERAL INFORMATION:
| Biological Significance | T cell protein tyrosine phosphatase (TCPTP), also known as PTPT and PTPN2, is an enzyme that removes phosphate groups covalently attached to tyrosine residues in proteins. TCPTP is ubiquitously expressed with particularly high expression in hematopoietic tissues and exists as two forms: an endoplasmic reticulum-targeted 48- kDa form (TC48) and a nuclear 45- kDa form (TC45). Although targeted to the nucleus, TC45 can exit in response to specific stimuli to dephosphorylate cytoplasmic substrates. TC-PTP is a negative regulator of the Jak/Stat cytokine signaling pathway. TCPTP is the PTP most closely related to PTP1B, with 72% sequence identity and 86% similarity in the catalytic domain. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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