Fitzgerald/TDG antibody/10R-8672/50 ul
商品编号：
10R-8672-50ul
品牌：
fitzgerald-fii
市场价：
¥3500.00
美元价：
2625.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | MonoclonalTDGantibody,TDGantibody,Thymine-DNAglycosylaseantibody,G/Tmismatch-specificthymineDNAglycosylaseantibody |
|---|---|
| Applications | ELISA,WB |
| Immunogen | TDGantibodywasraisedinMouseusingrecombinanthumanTDG(1-410aa)purifiedfromE.coliastheimmunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | AT2F7 |
| Isotype | IgG1kappa |
| MethodofPurification | TDGantibodywaspurifiedbyprotein-Aaffinitychromatography |
| Form&Buffer | SuppliedinliquidforminPhosphate-BufferedSaline(pH7.4)containing10%Glyceroland0.02%SodiumAzide |
| Concentration | 1mg/ml |
STORAGE&SAFETY:
| Storage | Canbestoredat4degCshortterm.Forlongtermstorage,aliquotandstoreat-20degC.Avoidrepeatedfreezingandthawingcycles. |
|---|
UsageAssayInformation:
| UsageRecommendations | ELISA:1:250,WB:1:250 |
|---|
GENERALINFORMATION:
| BIOLOGicalSignificance | G/Tmismatch-specificthymineDNAglycosylaseisanenzymethatinhumansisencodedbytheTDGgene.Severalbacterialproteinshavestrongsequencehomologywiththisprotein.TheproteinencodedbythisgenebelongstotheTDG/mugDNAglycosylasefamily.Thymine-DNAglycosylase(TDG)removesthyminemoietiesfromG/Tmismatchesbyhydrolyzingthecarbon-nitrogenbondbetweenthesugar-phosphatebackboneofDNAandthemispairedthymine.Withloweractivity,thisenzymealsoremovesthyminefromC/TandT/Tmispairings.TDGcanalsoremoveuraciland5-bromouracilfrommispairingswithguanine.Thisenzymeplaysacentralroleincellulardefenseagainstgeneticmutationcausedbythespontaneousdeaminationof5-methylcytosineandcytosine.Thisgenemayhaveapseudogeneintheparmofchromosome12. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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