Fitzgerald/HEXA antibody/10R-8681/50 ul
商品编号:
10R-8681-50ul
品牌:
fitzgerald-fii
市场价:
¥3900.00
美元价:
2925.00
产品分类:
功能性抗体
公司分类:
Functional_antibody
联系Q Q:
3392242852
电话号码:
4000-520-616
电子邮箱:
info@ebiomall.com
商品介绍
OVERVIEW:
Synonyms | Monoclonal HEXA antibody, Anti HEXA antibody, beta-hexosaminidase subunit alpha antibody, TSD antibody, hexosaminidase A antibody |
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Applications | ELISA, WB |
Immunogen | HEXA antibody was raised in Mouse using recombinant human HEXA (89-529aa) purified from E. coli as the immunogen |
SPECIFICATIONS:
Host | Mouse |
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Clone | AT20F1 |
Isotype | IgG2a lambda |
Method of Purification | HEXA antibody was purified by protein A affinity chromatography |
Form & Buffer | Supplied in liquid form in Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 0.02% Sodium Azide |
Concentration | 1 mg/ml |
Usage Assay Information:
Usage Recommendations | ELISA: 1:3000, WB: 1:3000 |
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GENERAL INFORMATION:
Biological Significance | HEXA (Hexosaminidase A), also designated beta-Hexosaminidase A, is responsible for the degradation of GM2 gangliosides, and a variety of other molecules containing terminal N-acetyl hexosamines, in the brain and other tissues. A mutation in the a subunit of hexosaminidase is the cause of Tay-Sachs disease (TSD), also known as GM2-gangliosidosis type I. TSD is a fatal autosomal recessive lysosomal storage disease of the central nervous system (CNS) caused by insufficient activity of the HEXA enzyme that results in a failure to process GM2 gangliosides. The accumulation of GM2 ganglioside in the absence of HEXA activity causes progressive destruction of the CNS. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种,能够满足您对于最前沿科学研究的需求。产品涉及:单克隆抗体/抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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