Fitzgerald/ICT1 antibody/10R-8685/50 ul
商品编号：
10R-8685-50ul
品牌：
fitzgerald-fii
市场价：
¥3900.00
美元价：
2925.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal ICT1 antibody, Anti ICT1 antibody, Peptidyl-tRNA hydrolase ICT1 mitochondrial antibody, DS-1 antibody, DS1 antibody |
|---|---|
| Applications | ELISA, WB |
| Immunogen | ICT1 antibody was raised in Mouse using recombinant human ICT1 (30-206aa) purified from E. coli as the immunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | AT1E9 |
| Isotype | IgG1 kappa |
| Method of Purification | ICT1 antibody was purified by protein A affinity chromatography |
| Form & Buffer | Supplied in liquid form in Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 0.02% Sodium Azide |
| Concentration | 1 mg/ml |
Usage Assay Information:
| Usage Recommendations | ELISA: 1:1000, WB: 1:1000 |
|---|
GENERAL INFORMATION:
| Biological Significance | Peptidyl-tRNA hydrolase ICT1 acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. The adult colon epithelium contains 3 differentiated cell types that arise from a multipotent stem cell. Deviation from the normal maturation pathway by neoplastic transformation is thought to initiate in stem cells or their early descendants. This neoplastic-induced deviation is marked by a change in expression of several mRNAs. ICT1 is a member of the prokaryotic/mitochondrial release factor family whose expression is downregulated over 4 fold upon colon stem cell differentiation. This downregulation of ICT1 could lead to its use as a marker for detection of colon carcinomas. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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