菲茨杰拉德/血管生成素2抗体/10-2265/100微克
商品编号：
10-2265-100ug
品牌：
fitzgerald-fii
市场价：
¥7000.00
美元价：
5250.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | MonoclonalAngiopoietin2antibody,Anti-Angiopoietin2antibody,angiopoietin-2aantibody,angiopoietin-2Bantibody,ANGP2antibody,ANGPT2antibody,Tie2-ligandantibody,AGPT2antibody,ANG-2antibody,ANG2antibody,angiopoietin2antibody,Angiopoietin-2antibody |
|---|---|
| Specificity | Human |
| ProteinType | Recombinant |
| Applications | ELISA |
| AssayInformation | Angiopoietin2antibodypair:10-2264canbeusedasthecaptureantibodywith10-2265asthedetectionantibodyfordetectionofhumanAngiopoietin2inELISA |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | M72048 |
| Isotype | IgG1kappa-Fabfragment |
| ExpressionSystem | E.coli |
| Purity | >95%pure |
| MethodofPurification | Angiopoietin2antibodiesscreenedusingPhageDisplaysystem.ExpressedinandpurifiedfromE.coli. |
| Tag/Conjugate | Histag |
| Form&Buffer | Suppliedasliquidin50mMPotassiumPhosphate,10mMBoricAcid,150mMNaCl,pH7 |
| Concentration | >1mg/ml |
STORAGE&SAFETY:
| Storage | Storeat-20degCinsmallaliquots.Avoidrepeatedfreezethawing. |
|---|
GENERALINFORMATION:
| BIOLOGicalSignificance | Angiopoietin2bindstoTEK/TIE2,competingfortheANGPT1bindingsite,andmodulatingANGPT1signaling.CaninducetyrosinephosphorylationofTEK/TIE2intheabsenceofANGPT1.Intheabsenceofangiogenicinducers,suchasVEGF,ANGPT2-mediatedlooseningofcell-matrixcontactsmayinduceendothelialcellapoptosiswithconsequentvascularregression.InconcertwithVEGF,itmayfacilitateendothelialcellmigrationandproliferation,thusservingasapermissiveangiogenicsignal.Angiopoietin2antibodywasproducedasarecombinantFabmonoclonalantibodyinaPhageDisplaysystem.Thisanti-Angiopoietin2antibodyisusedfordetectionofhumanAngiopoietin2inELISA.Theconcentrationoftheantibodyrangesfrom1mg/mlto25mg/mldependingonthelot.RecombinantFabmonoclonalantibodieshaveanumberofadvantagesoverstandardantibodiesincluding;improvedscaleupforbatchconsistency,moreefficientbindingsolessantibodyrequired,moreaccuratebindingmeaningfewerconjugationissues,lessnonspecificduetoremovaloftheFcregion,moreflexibilityforpurificationandlabelingthroughaC-terminalHistag. |
|---|
品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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