Fitzgerald/EPCAM antibody/10R-10258/50 ul
商品编号：
10R-10258-50ul
品牌：
fitzgerald-fii
市场价：
¥3500.00
美元价：
2625.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
OVERVIEW:
| Synonyms | Monoclonal EPCAM antibody , Anti EPCAM antibody , Epithelial cell adhesion molecules antibody, CD326 antibody, KS1/4 antibody, KSA antibody, M4S1 antibody, MIC18 antibody, MK-1 antibody, TACSTD1 antibody, TROP1 antibody, DIAR5 antibody, EGP antibody, GA733 2 antibody, HNPCC8 antibody |
|---|---|
| Specificity | Human |
| Applications | ELISA, WB |
| Immunogen | EPCAM antibody was raised in mouse using recombinant human EPCAM (24-265aa) purified from E. coli as the immunogen |
SPECIFICATIONS:
| Host | Mouse |
|---|---|
| Clone | AT37F9 |
| Isotype | IgG1,k |
| Source | EPCAM antibody is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human EPCAM protein. |
| Method of Purification | EPCAM antibody is purified by Protein A affinity chromatography |
| Form & Buffer | Supplied as liquid in PBS (pH 7.4) containing 10% glycerol, 0.02% NaN3. |
| Concentration | 1 mg/ml |
STORAGE & SAFETY:
| Storage | Store at 4 deg C short term. For long term storage, aliquot and store at -20 deg C and avoid repeated freeze/thaw cycles. |
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Usage Assay Information:
| Usage Recommendations | Recommended starting dilution is 1:1000 |
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GENERAL INFORMATION:
| Biological Significance | Epithelial cell adhesion molecule (EPCAM) is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell-cell adhesion in epithelia. EPCAM is also involved in cell signaling, migration, proliferation, and differentiation. Additionally, EPCAM has oncogenic potential via its capacity to upregulate c-myc, e-fabp, and cyclins A & E. Since EPCAM is expressed exclusively in epithelia and epithelial-derived neoplasms, EPCAM can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies. |
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品牌介绍
美国Fitzgerald 公司是一家国际性知名抗体研发生产企业。Fitzgerald公司为全球试剂诊断公司与研究机构提供专业的抗体、纯化抗原以及工业诊断用大包装免疫原料。公司产品多达5000种，能够满足您对于最前沿科学研究的需求。产品涉及：单克隆抗体／抗原生育类、传染病类、TORCH系列、肿瘤标记物、心脏标记物、神经科学类、病毒类等等。
品牌分类
重组蛋白
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